Cargando…
Chemical Analysis and Transplacental Transfer of Oseltamivir and Oseltamivir Carboxylic Acid in Pregnant Rats
In view of the limited information on the pharmacokinetics of oseltamivir (OSE) during pregnancy, this study aims to evaluate the placental transportation of OSE and its active metabolite oseltamivir carboxylic acid (OCA) in rats. A validated liquid chromatography-tandem mass spectrometry (LC-MS/MS)...
Autores principales: | Lin, Chia-Chun, Yen, Jiin-Cherng, Wu, Yu-Tse, Lin, Lie-Chwen, Tsai, Tung-Hu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463610/ https://www.ncbi.nlm.nih.gov/pubmed/23056234 http://dx.doi.org/10.1371/journal.pone.0046062 |
Ejemplares similares
-
The Metabolism and Transplacental Transfer of Oseltamivir in the Ex Vivo Human Model
por: Worley, Kevin C., et al.
Publicado: (2008) -
Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS-441524 in pregnant rats
por: Yang, Ling, et al.
Publicado: (2022) -
Population pharmacokinetics of oseltamivir and oseltamivir carboxylate in obese and non‐obese volunteers
por: Chairat, Kalayanee, et al.
Publicado: (2016) -
Plasma Concentrations of Oseltamivir and Oseltamivir Carboxylate in Critically Ill Children on Extracorporeal Membrane Oxygenation Support
por: Wildschut, Enno D., et al.
Publicado: (2010) -
An in vitro study of elimination of oseltamivir carboxylate by haemofiltration
por: Gruber, P, et al.
Publicado: (2007)