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Evaluation of Different Reference Based Annotation Strategies Using RNA-Seq – A Case Study in Drososphila pseudoobscura

RNA-Seq is a powerful tool for the annotation of genomes, in particular for the identification of isoforms and UTRs. Nevertheless, several software tools exist and no standard strategy to obtain a reliable annotation is yet established. We tested different combinations of the most commonly used refe...

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Detalles Bibliográficos
Autores principales: Palmieri, Nicola, Nolte, Viola, Suvorov, Anton, Kosiol, Carolin, Schlötterer, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463616/
https://www.ncbi.nlm.nih.gov/pubmed/23056304
http://dx.doi.org/10.1371/journal.pone.0046415