PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

NETosis, the process wherein neutrophils release highly decondensed chromatin called neutrophil extracellular traps (NETs), has gained much attention as an alternative means of killing bacteria. In vivo, NETs are induced by bacteria and pro-inflammatory cytokines. We have reported that peptidylargin...

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Detalles Bibliográficos
Autores principales: Leshner, Marc, Wang, Shu, Lewis, Carrie, Zheng, Han, Chen, Xiangyun Amy, Santy, Lorraine, Wang, Yanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463874/
https://www.ncbi.nlm.nih.gov/pubmed/23060885
http://dx.doi.org/10.3389/fimmu.2012.00307

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