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Behavioral interactions of simvastatin and fluoxetine in tests of anxiety and depression
Simvastatin inhibits 3-hydroxy-3-methylglutaryl CoA reductase, the rate-limiting enzyme in the cholesterol biosynthetic pathway, and is widely used to control plasma cholesterol levels and prevent cardiovascular disease. However, emerging evidence indicates that the beneficial effects of simvastatin...
Autores principales: | Santos, Tainaê, Baungratz, Monaliza Marizete, Haskel, Suellen Priscila, de Lima, Daniela Delwing, da Cruz, Júlia Niehues, Magro, Débora Delwing Dal, da Cruz, José Geraldo Pereira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464062/ https://www.ncbi.nlm.nih.gov/pubmed/23055736 http://dx.doi.org/10.2147/NDT.S31714 |
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