Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation

BACKGROUND: Neuroinflammation, caused by six days of intracerebroventricular infusion of bacterial lipopolysaccharide (LPS), stimulates rat brain arachidonic acid (AA) metabolism. The molecular changes associated with increased AA metabolism are not clear. We examined effects of a six-day infusion o...

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Detalles Bibliográficos
Autores principales: Kellom, Matthew, Basselin, Mireille, Keleshian, Vasken L, Chen, Mei, Rapoport, Stanley I, Rao, Jagadeesh S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464147/
https://www.ncbi.nlm.nih.gov/pubmed/22621398
http://dx.doi.org/10.1186/1471-2202-13-50

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