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Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia
BACKGROUND: A considerable proportion of all newly generated cells in the hippocampus will die before becoming fully differentiated, both under normal and pathological circumstances. The caspase-independent apoptosis-inducing factor (AIF) has not been investigated previously in this context. RESULTS...
Autores principales: | Sun, Yanyan, Zhang, Yu, Wang, Xiaoyang, Blomgren, Klas, Zhu, Changlian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464153/ https://www.ncbi.nlm.nih.gov/pubmed/22534064 http://dx.doi.org/10.1186/1750-1326-7-17 |
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