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Random Field Model Reveals Structure of the Protein Recombinational Landscape

We are interested in how intragenic recombination contributes to the evolution of proteins and how this mechanism complements and enhances the diversity generated by random mutation. Experiments have revealed that proteins are highly tolerant to recombination with homologous sequences (mutation by r...

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Detalles Bibliográficos
Autores principales: Romero, Philip A., Arnold, Frances H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464211/
https://www.ncbi.nlm.nih.gov/pubmed/23055915
http://dx.doi.org/10.1371/journal.pcbi.1002713

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