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Random Field Model Reveals Structure of the Protein Recombinational Landscape
We are interested in how intragenic recombination contributes to the evolution of proteins and how this mechanism complements and enhances the diversity generated by random mutation. Experiments have revealed that proteins are highly tolerant to recombination with homologous sequences (mutation by r...
Autores principales: | Romero, Philip A., Arnold, Frances H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464211/ https://www.ncbi.nlm.nih.gov/pubmed/23055915 http://dx.doi.org/10.1371/journal.pcbi.1002713 |
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