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Split-Doa10: A Naturally Split Polytopic Eukaryotic Membrane Protein Generated by Fission of a Nuclear Gene

Large polytopic membrane proteins often derive from duplication and fusion of genes for smaller proteins. The reverse process, splitting of a membrane protein by gene fission, is rare and has been studied mainly with artificially split proteins. Fragments of a split membrane protein may associate an...

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Detalles Bibliográficos
Autores principales: Stuerner, Elisabeth, Kuraku, Shigehiro, Hochstrasser, Mark, Kreft, Stefan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464245/
https://www.ncbi.nlm.nih.gov/pubmed/23071509
http://dx.doi.org/10.1371/journal.pone.0045194