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Dysfunctional Behavioral Modulation of Corticostriatal Communication in the R6/2 Mouse Model of Huntington’s Disease

BACKGROUND: In Huntington’s disease (HD), motor symptoms develop prior to the widespread loss of neurons in striatum and cerebral cortex. The aim of this study was to examine dysfunctional patterns of corticostriatal communication during spontaneously occurring behaviors in a transgenic mouse model...

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Detalles Bibliográficos
Autores principales:	Hong, S. Lee, Cossyleon, Desirée, Hussain, Wajeeha A., Walker, Lauren J., Barton, Scott J., Rebec, George V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464283/ https://www.ncbi.nlm.nih.gov/pubmed/23056565 http://dx.doi.org/10.1371/journal.pone.0047026

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