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Activation of the Connective Tissue Growth Factor (CTGF)-Transforming Growth Factor β 1 (TGF-β 1) Axis in Hepatitis C Virus-Expressing Hepatocytes

BACKGROUND: The pro-fibrogenic cytokine connective tissue growth factor (CTGF) plays an important role in the development and progression of fibrosis in many organ systems, including liver. However, its role in the pathogenesis of hepatitis C virus (HCV)-induced liver fibrosis remains unclear. METHO...

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Detalles Bibliográficos
Autores principales:	Nagaraja, Tirumuru, Chen, Li, Balasubramanian, Anuradha, Groopman, Jerome E., Ghoshal, Kalpana, Jacob, Samson T., Leask, Andrew, Brigstock, David R., Anand, Appakkudal R., Ganju, Ramesh K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464290/ https://www.ncbi.nlm.nih.gov/pubmed/23056332 http://dx.doi.org/10.1371/journal.pone.0046526

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