Transgelin 2 Participates in Lovastatin-Induced Anti-Angiogenic Effects in Endothelial Cells through a Phosphorylated Myosin Light Chain-Related Mechanism

BACKGROUND: Anti-angiogenic activity is considered to play a key role in the statin-induced anti-tumor effects. We aimed to identify new targets underlying this pleiotropic effect of lovastatin. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the inhibitory effects of lovastatin on endothelial cell...

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Detalles Bibliográficos
Autores principales: Xiao, Yuan, Li, Yuhua, Han, Jing, Pan, Yan, Tie, Lu, Li, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464299/
https://www.ncbi.nlm.nih.gov/pubmed/23056327
http://dx.doi.org/10.1371/journal.pone.0046510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464299/
https://www.ncbi.nlm.nih.gov/pubmed/23056327
http://dx.doi.org/10.1371/journal.pone.0046510

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