A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer

Radioiodine is regularly used in the treatment of thyroid cancer to eliminate residual malignant tissue after thyroidectomy and to treat metastasis. Because of the low dose of radioiodine used to treat thyroid cancer patients, leukemia is an uncommon complication of exposure to radioiodine. Here, we...

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Autores principales: Jeong, Ji Hun, Ahn, Jeong Yeal, Park, Soon Ho, Park, Mi Jung, Kim, Kyung Hee, Hong, Jun Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464341/
https://www.ncbi.nlm.nih.gov/pubmed/23071479
http://dx.doi.org/10.5045/kjh.2012.47.3.225
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author Jeong, Ji Hun
Ahn, Jeong Yeal
Park, Soon Ho
Park, Mi Jung
Kim, Kyung Hee
Hong, Jun Shik
author_facet Jeong, Ji Hun
Ahn, Jeong Yeal
Park, Soon Ho
Park, Mi Jung
Kim, Kyung Hee
Hong, Jun Shik
author_sort Jeong, Ji Hun
collection PubMed
description Radioiodine is regularly used in the treatment of thyroid cancer to eliminate residual malignant tissue after thyroidectomy and to treat metastasis. Because of the low dose of radioiodine used to treat thyroid cancer patients, leukemia is an uncommon complication of exposure to radioiodine. Here, we present a patient who developed therapy-related acute myeloid leukemia with inv(16)(p13.1q22);CBFβ-MYH11, eosinophilia, and K-ras mutation and who had been treated with very low-dose radioiodine following total thyroidectomy.
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spelling pubmed-34643412012-10-15 A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer Jeong, Ji Hun Ahn, Jeong Yeal Park, Soon Ho Park, Mi Jung Kim, Kyung Hee Hong, Jun Shik Korean J Hematol Case Report Radioiodine is regularly used in the treatment of thyroid cancer to eliminate residual malignant tissue after thyroidectomy and to treat metastasis. Because of the low dose of radioiodine used to treat thyroid cancer patients, leukemia is an uncommon complication of exposure to radioiodine. Here, we present a patient who developed therapy-related acute myeloid leukemia with inv(16)(p13.1q22);CBFβ-MYH11, eosinophilia, and K-ras mutation and who had been treated with very low-dose radioiodine following total thyroidectomy. Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2012-09 2012-09-25 /pmc/articles/PMC3464341/ /pubmed/23071479 http://dx.doi.org/10.5045/kjh.2012.47.3.225 Text en © 2012 Korean Society of Hematology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jeong, Ji Hun
Ahn, Jeong Yeal
Park, Soon Ho
Park, Mi Jung
Kim, Kyung Hee
Hong, Jun Shik
A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
title A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
title_full A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
title_fullStr A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
title_full_unstemmed A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
title_short A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
title_sort case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464341/
https://www.ncbi.nlm.nih.gov/pubmed/23071479
http://dx.doi.org/10.5045/kjh.2012.47.3.225
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