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Phosphoinositide-3-kinase/akt - dependent signaling is required for maintenance of [Ca(2+)](i,)I(Ca), and Ca(2+) transients in HL-1 cardiomyocytes

The phosphoinositide 3-kinases (PI3K/Akt) dependent signaling pathway plays an important role in cardiac function, specifically cardiac contractility. We have reported that sepsis decreases myocardial Akt activation, which correlates with cardiac dysfunction in sepsis. We also reported that preventi...

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Detalles Bibliográficos
Autores principales:	Graves, Bridget M, Simerly, Thomas, Li, Chuanfu, Williams, David L, Wondergem, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464604/ https://www.ncbi.nlm.nih.gov/pubmed/22715995 http://dx.doi.org/10.1186/1423-0127-19-59

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