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Protective role of 1,25(OH)(2)vitamin D(3) in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice
BACKGROUND: Intestinal hyper-permeability plays a critical role in the etiopathogenesis of inflammatory bowel disease (IBD) by affecting the penetration of pathogens, toxic compounds and macromolecules. 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], the active form of vitamin D, has been shown to be...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464614/ https://www.ncbi.nlm.nih.gov/pubmed/22647055 http://dx.doi.org/10.1186/1471-230X-12-57 |