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Protective role of 1,25(OH)(2)vitamin D(3) in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice

BACKGROUND: Intestinal hyper-permeability plays a critical role in the etiopathogenesis of inflammatory bowel disease (IBD) by affecting the penetration of pathogens, toxic compounds and macromolecules. 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], the active form of vitamin D, has been shown to be...

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Detalles Bibliográficos
Autores principales:	Zhao, Hongwei, Zhang, Hong, Wu, Hui, Li, Hui, Liu, Lei, Guo, Jian, Li, Chenyang, Shih, David Q, Zhang, Xiaolan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464614/ https://www.ncbi.nlm.nih.gov/pubmed/22647055 http://dx.doi.org/10.1186/1471-230X-12-57

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