Cargando…

Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target

Heat shock protein 27 (HSP27) is a multidimensional protein which acts as a protein chaperone and an antioxidant and plays a role in the inhibition of apoptosis and actin cytoskeletal remodeling. In each of these capacities, HSP27 has been implicated in different disease states playing both protecti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vidyasagar, Aparna, Wilson, Nancy A, Djamali, Arjang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464729/ https://www.ncbi.nlm.nih.gov/pubmed/22564335 http://dx.doi.org/10.1186/1755-1536-5-7

Ejemplares similares

Tubular expression of heat shock protein 27 inhibits fibrogenesis in obstructive nephropathy
por: Vidyasagar, Aparna, et al.
Publicado: (2012)

Localization of Heat Shock Protein 27 (Hsp27) in the Rat Gingiva and its Changes with Tooth Eruption
por: Sasaki, Au, et al.
Publicado: (2011)

Revisiting the Old Data of Heat Shock Protein 27 Expression in Squamous Cell Carcinoma: Enigmatic HSP27, More Than Heat Shock
por: Zheng, Shutao, et al.
Publicado: (2022)

Proteomic Characterization of Annexin l (ANX1) and Heat Shock Protein 27 (HSP27) as Biomarkers for Invasive Hepatocellular Carcinoma Cells
por: Wang, Ruo-Chiau, et al.
Publicado: (2015)

Expression of Heat Shock Protein-27 (Hsp27) and P38MAPK in Esophageal Squamous Cell Carcinoma
por: Zhang, Yan, et al.
Publicado: (2017)

The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
por: Boyd, Rowan A., et al.
Publicado: (2023)

Heat‐shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF
por: Konda, John D., et al.
Publicado: (2017)

Could Small Heat Shock Protein HSP27 Be a First-Line Target for Preventing Protein Aggregation in Parkinson’s Disease?
por: Navarro-Zaragoza, Javier, et al.
Publicado: (2021)

Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo
por: Gibert, B, et al.
Publicado: (2012)

Tissue-specific expression of the heat shock protein HSP27 during Drosophila melanogaster development
Publicado: (1990)

Mechanistic insights into heat shock protein 27, a potential therapeutic target for cardiovascular diseases
por: Zou, Yifei, et al.
Publicado: (2023)

Overexpression of heat shock protein 27 (HSP27) increases gemcitabine sensitivity in pancreatic cancer cells through S-phase arrest and apoptosis
por: Guo, Yang, et al.
Publicado: (2015)

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells
Publicado: (1989)

Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity
por: Mukherjee, Somnath, et al.
Publicado: (2023)

Heat Shock Protein 27 (HSP27) as a Potential Prognostic Marker: Immunohistochemical Analysis of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma
por: Ramalingam, Karthikeyan, et al.
Publicado: (2022)

Clinical, prognostic, and therapeutic significance of heat shock protein 27 in bladder cancer
por: Lee, Myung-Shin, et al.
Publicado: (2018)

Clinicopathological Significance of Heat Shock Protein (HSP) 27 Expression in Gastric Cancer: A Updated Meta-Analysis
por: Liu, Tong, et al.
Publicado: (2020)

Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins
por: Gibert, Benjamin, et al.
Publicado: (2012)

Serum levels of phosphorylated heat shock protein 27 (pHSP27) are associated with bone mineral density in pre- & postmenopausal women: A pilot study
por: Daswani, Bhavna, et al.
Publicado: (2016)

Clinicopathological and prognostic significance of heat shock protein 27 (HSP27) expression in non-small cell lung cancer: a systematic review and meta-analysis
por: Li, Shuangjiang, et al.
Publicado: (2016)

Heat Shock Protein HSP27 Secretion by Ovarian Cancer Cells Is Linked to Intracellular Expression Levels, Occurs Independently of the Endoplasmic Reticulum Pathway and HSP27's Phosphorylation Status, and Is Mediated by Exosome Liberation
por: Stope, Matthias B., et al.
Publicado: (2017)

Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment?
por: Choi, Seul-Ki, et al.
Publicado: (2019)

Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma
por: Schäfer, Claus, et al.
Publicado: (2012)

Effect of Heat Shock Preconditioning on Pressure Injury Prevention via Hsp27 Upregulation in Rat Models
por: Xu, Huiwen, et al.
Publicado: (2022)

Heat Shock Protein27 Expression and Cell Differentiation in Ameloblastomas
por: Fujita, Muneteru, et al.
Publicado: (2013)

Insights Into the Role of Heat Shock Protein 27 in the Development of Neurodegeneration
por: Holguin, Bianka A., et al.
Publicado: (2022)

Expression of Inducible Heat Shock Proteins Hsp27 and Hsp70 in the Visual Pathway of Rats Subjected to Various Models of Retinal Ganglion Cell Injury
por: Chidlow, Glyn, et al.
Publicado: (2014)

Differential Expression of Heat Shock Protein 27 in Oral Epithelial Dysplasias and Squamous Cell Carcinoma
por: Karri, Roja Lakshmi, et al.
Publicado: (2020)

Heat Shock Protein 90 (Hsp90) and Hsp70 as Potential Therapeutic Targets in Autoimmune Skin Diseases
por: Tukaj, Stefan, et al.
Publicado: (2022)

The Effect of Oxidized Dopamine on the Structure and Molecular Chaperone Function of the Small Heat-Shock Proteins, αB-Crystallin and Hsp27
por: Hayashi, Junna, et al.
Publicado: (2021)

Expression of one important chaperone protein, heat shock protein 27, in neurodegenerative diseases
por: Zhang, Xuekai, et al.
Publicado: (2014)

Hsp27-Actin Interaction
por: Graceffa, Philip
Publicado: (2011)

Heat shock protein 27 phosphorylation state is associated with cancer progression
por: Katsogiannou, Maria, et al.
Publicado: (2014)

The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer
por: Okuno, Mitsuru, et al.
Publicado: (2016)

The Role of Heat Shock Protein 27 in Carcinogenesis and Treatment of Colorectal Cancer
por: Asgharzadeh, Fereshteh, et al.
Publicado: (2022)

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules
por: Kim, Jee Hye, et al.
Publicado: (2016)

Effect of N-terminal region of nuclear Drosophila melanogaster small heat shock protein DmHsp27 on function and quaternary structure
por: Moutaoufik, Mohamed Taha, et al.
Publicado: (2017)

Heat shock proteins (HSP 90, 70, 60, and 27) in Galleria mellonella (Lepidoptera) hemolymph are affected by infection with Conidiobolus coronatus (Entomophthorales)
por: Wrońska, Anna Katarzyna, et al.
Publicado: (2020)

The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration
por: Schwarz, Lisa, et al.
Publicado: (2010)

Significance of unphosphorylated and phosphorylated heat shock protein 27 as a prognostic biomarker in pancreatic ductal adenocarcinoma
por: Drexler, Richard, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k2gpdoa7q7ceobcuq3liur49cm