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Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer
BACKGROUND: Few epidemiological studies have prospectively investigated preoperative and surgical risk factors for acute postoperative pain after surgery for breast cancer. We investigated demographic, psychological, pain-related and surgical risk factors in women undergoing resectional surgery for...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464763/ https://www.ncbi.nlm.nih.gov/pubmed/22850552 http://dx.doi.org/10.1038/bjc.2012.341 |
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author | Bruce, J Thornton, A J Scott, N W Marfizo, S Powell, R Johnston, M Wells, M Heys, S D Thompson, A M |
author_facet | Bruce, J Thornton, A J Scott, N W Marfizo, S Powell, R Johnston, M Wells, M Heys, S D Thompson, A M |
author_sort | Bruce, J |
collection | PubMed |
description | BACKGROUND: Few epidemiological studies have prospectively investigated preoperative and surgical risk factors for acute postoperative pain after surgery for breast cancer. We investigated demographic, psychological, pain-related and surgical risk factors in women undergoing resectional surgery for breast cancer. METHODS: Primary outcomes were pain severity, at rest (PAR) and movement-evoked pain (MEP), in the first postoperative week. RESULTS: In 338 women undergoing surgery, those with chronic preoperative pain were three times more likely to report moderate to severe MEP after breast cancer surgery (OR 3.18, 95% CI 1.45–6.99). Increased psychological ‘robustness’, a composite variable representing positive affect and dispositional optimism, was associated with lower intensity acute postoperative PAR (OR 0.63, 95% CI 0.48–0.82) and MEP (OR 0.71, 95% CI 0.54–0.93). Sentinel lymph node biopsy (SLNB) and intraoperative nerve division were associated with reduced postoperative pain. No relationship was found between preoperative neuropathic pain and acute pain outcomes; altered sensations and numbness postoperatively were more common after axillary sample or clearance compared with SLNB. CONCLUSION: Chronic preoperative pain, axillary surgery and psychological robustness significantly predicted acute pain outcomes after surgery for breast cancer. Preoperative identification and targeted intervention of subgroups at risk could enhance the recovery trajectory in cancer survivors. |
format | Online Article Text |
id | pubmed-3464763 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-34647632013-09-04 Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer Bruce, J Thornton, A J Scott, N W Marfizo, S Powell, R Johnston, M Wells, M Heys, S D Thompson, A M Br J Cancer Clinical Study BACKGROUND: Few epidemiological studies have prospectively investigated preoperative and surgical risk factors for acute postoperative pain after surgery for breast cancer. We investigated demographic, psychological, pain-related and surgical risk factors in women undergoing resectional surgery for breast cancer. METHODS: Primary outcomes were pain severity, at rest (PAR) and movement-evoked pain (MEP), in the first postoperative week. RESULTS: In 338 women undergoing surgery, those with chronic preoperative pain were three times more likely to report moderate to severe MEP after breast cancer surgery (OR 3.18, 95% CI 1.45–6.99). Increased psychological ‘robustness’, a composite variable representing positive affect and dispositional optimism, was associated with lower intensity acute postoperative PAR (OR 0.63, 95% CI 0.48–0.82) and MEP (OR 0.71, 95% CI 0.54–0.93). Sentinel lymph node biopsy (SLNB) and intraoperative nerve division were associated with reduced postoperative pain. No relationship was found between preoperative neuropathic pain and acute pain outcomes; altered sensations and numbness postoperatively were more common after axillary sample or clearance compared with SLNB. CONCLUSION: Chronic preoperative pain, axillary surgery and psychological robustness significantly predicted acute pain outcomes after surgery for breast cancer. Preoperative identification and targeted intervention of subgroups at risk could enhance the recovery trajectory in cancer survivors. Nature Publishing Group 2012-09-04 2012-07-31 /pmc/articles/PMC3464763/ /pubmed/22850552 http://dx.doi.org/10.1038/bjc.2012.341 Text en Copyright © 2012 Cancer Research UK https://creativecommons.org/licenses/by-nc-sa/3.0/From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
spellingShingle | Clinical Study Bruce, J Thornton, A J Scott, N W Marfizo, S Powell, R Johnston, M Wells, M Heys, S D Thompson, A M Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer |
title | Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer |
title_full | Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer |
title_fullStr | Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer |
title_full_unstemmed | Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer |
title_short | Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer |
title_sort | chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464763/ https://www.ncbi.nlm.nih.gov/pubmed/22850552 http://dx.doi.org/10.1038/bjc.2012.341 |
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