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Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population
BACKGROUND: Prior to the present study, the seroprevalence of leptospirosis in Irish suckler herds was unknown. In this study, we describe the herd and animal-level prevalence of Leptospira Hardjo infection in the Irish suckler cattle population. For the purposes of the study, the 26 counties of the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464776/ https://www.ncbi.nlm.nih.gov/pubmed/22546216 http://dx.doi.org/10.1186/2046-0481-65-8 |
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author | Ryan, Eoin Gerard Leonard, Nola O’Grady, Luke More, Simon J Doherty, Michael L |
author_facet | Ryan, Eoin Gerard Leonard, Nola O’Grady, Luke More, Simon J Doherty, Michael L |
author_sort | Ryan, Eoin Gerard |
collection | PubMed |
description | BACKGROUND: Prior to the present study, the seroprevalence of leptospirosis in Irish suckler herds was unknown. In this study, we describe the herd and animal-level prevalence of Leptospira Hardjo infection in the Irish suckler cattle population. For the purposes of the study, the 26 counties of the Republic of Ireland were divided into 6 regions from which a representative number of herds were selected. A herd was considered eligible for sampling if it was not vaccinating against leptospirosis and if it contained ≥ 9 breeding animals of beef breed ≥ 12 months of age. In total, 288 randomly selected herds were eligible for inclusion in the seroprevalence dataset analysis. Serological testing was carried out using a commercially available monoclonal antibody-capture ELISA, (sensitivity 100%; specificity 86.67%). RESULTS: Herds were categorised as either “Free from Infection” or “Infected” using the epidemiological software tool, FreeCalc 2.0. Using this classification, 237 herds were “Infected” (82.29%). The South West and South East regions had the highest herd prevalence. The regional effect on herd prevalence was largely mirrored by breeding herd size. A true animal-level prevalence of 41.75% was calculated using the epidemiological software tool, TruePrev. There was a statistically significant regional trend, with true prevalence being highest in the South East (P < 0.05). The median Breeding Herd Size (BHS), when categorised into quartiles, had a statistically significant influence on individual animal true seroprevalence (P < 0.001); true seroprevalence increased with increasing BHS. CONCLUSIONS: Leptospirosis is a widespread endemic disease in the Republic of Ireland. It is possible that economic losses due to leptospirosis in unvaccinated Irish suckler herds may be underestimated. |
format | Online Article Text |
id | pubmed-3464776 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34647762012-10-05 Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population Ryan, Eoin Gerard Leonard, Nola O’Grady, Luke More, Simon J Doherty, Michael L Ir Vet J Research BACKGROUND: Prior to the present study, the seroprevalence of leptospirosis in Irish suckler herds was unknown. In this study, we describe the herd and animal-level prevalence of Leptospira Hardjo infection in the Irish suckler cattle population. For the purposes of the study, the 26 counties of the Republic of Ireland were divided into 6 regions from which a representative number of herds were selected. A herd was considered eligible for sampling if it was not vaccinating against leptospirosis and if it contained ≥ 9 breeding animals of beef breed ≥ 12 months of age. In total, 288 randomly selected herds were eligible for inclusion in the seroprevalence dataset analysis. Serological testing was carried out using a commercially available monoclonal antibody-capture ELISA, (sensitivity 100%; specificity 86.67%). RESULTS: Herds were categorised as either “Free from Infection” or “Infected” using the epidemiological software tool, FreeCalc 2.0. Using this classification, 237 herds were “Infected” (82.29%). The South West and South East regions had the highest herd prevalence. The regional effect on herd prevalence was largely mirrored by breeding herd size. A true animal-level prevalence of 41.75% was calculated using the epidemiological software tool, TruePrev. There was a statistically significant regional trend, with true prevalence being highest in the South East (P < 0.05). The median Breeding Herd Size (BHS), when categorised into quartiles, had a statistically significant influence on individual animal true seroprevalence (P < 0.001); true seroprevalence increased with increasing BHS. CONCLUSIONS: Leptospirosis is a widespread endemic disease in the Republic of Ireland. It is possible that economic losses due to leptospirosis in unvaccinated Irish suckler herds may be underestimated. BioMed Central 2012-04-30 /pmc/articles/PMC3464776/ /pubmed/22546216 http://dx.doi.org/10.1186/2046-0481-65-8 Text en Copyright ©2012 Ryan et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Ryan, Eoin Gerard Leonard, Nola O’Grady, Luke More, Simon J Doherty, Michael L Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population |
title | Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population |
title_full | Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population |
title_fullStr | Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population |
title_full_unstemmed | Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population |
title_short | Seroprevalence of Leptospira Hardjo in the Irish suckler cattle population |
title_sort | seroprevalence of leptospira hardjo in the irish suckler cattle population |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464776/ https://www.ncbi.nlm.nih.gov/pubmed/22546216 http://dx.doi.org/10.1186/2046-0481-65-8 |
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