Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report

INTRODUCTION: Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problems, gastrointestinal perforation, proteinuria and hypert...

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Autores principales: Uysal, Mukremin, Goksu, Sema Sezgin, Coskun, Hasan Senol, Savas, Burhan, Ozdogan, Mustafa, Bozcuk, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464779/
https://www.ncbi.nlm.nih.gov/pubmed/22776219
http://dx.doi.org/10.1186/1752-1947-6-188
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author Uysal, Mukremin
Goksu, Sema Sezgin
Coskun, Hasan Senol
Savas, Burhan
Ozdogan, Mustafa
Bozcuk, Hakan
author_facet Uysal, Mukremin
Goksu, Sema Sezgin
Coskun, Hasan Senol
Savas, Burhan
Ozdogan, Mustafa
Bozcuk, Hakan
author_sort Uysal, Mukremin
collection PubMed
description INTRODUCTION: Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problems, gastrointestinal perforation, proteinuria and hypertension. CASE PRESENTATION: We present the case of a 65-year old Asian man with synovial metastasis of the knee who experienced intraarticular hemorrhage after bevacizumab treatment. He presented with monoarthritis of the left knee. CONCLUSION: Bevacizumab-related hemorrhage can cause serious morbidity and unusual sites of hemorrhage may be seen.
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spelling pubmed-34647792012-10-05 Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report Uysal, Mukremin Goksu, Sema Sezgin Coskun, Hasan Senol Savas, Burhan Ozdogan, Mustafa Bozcuk, Hakan J Med Case Rep Case Report INTRODUCTION: Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problems, gastrointestinal perforation, proteinuria and hypertension. CASE PRESENTATION: We present the case of a 65-year old Asian man with synovial metastasis of the knee who experienced intraarticular hemorrhage after bevacizumab treatment. He presented with monoarthritis of the left knee. CONCLUSION: Bevacizumab-related hemorrhage can cause serious morbidity and unusual sites of hemorrhage may be seen. BioMed Central 2012-07-09 /pmc/articles/PMC3464779/ /pubmed/22776219 http://dx.doi.org/10.1186/1752-1947-6-188 Text en Copyright ©2012 Uysal et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Uysal, Mukremin
Goksu, Sema Sezgin
Coskun, Hasan Senol
Savas, Burhan
Ozdogan, Mustafa
Bozcuk, Hakan
Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_full Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_fullStr Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_full_unstemmed Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_short Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_sort intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464779/
https://www.ncbi.nlm.nih.gov/pubmed/22776219
http://dx.doi.org/10.1186/1752-1947-6-188
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