Cargando…

Cytotoxic CD8(+) T cells and CD138(+) plasma cells prevail in cerebrospinal fluid in non-paraneoplastic cerebellar ataxia with contactin-associated protein-2 antibodies

OBJECTIVE: The purpose of this paper is to report a patient with otherwise unexplained cerebellar ataxia with serum antibodies against contactin-associated protein-2 (CASPR-2) and provide a detailed description of the composition of cellular infiltrates in the cerebrospinal fluid (CSF) compared to t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Melzer, Nico, Golombeck, Kristin S, Gross, Catharina C, Meuth, Sven G, Wiendl, Heinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464990/ https://www.ncbi.nlm.nih.gov/pubmed/22759321 http://dx.doi.org/10.1186/1742-2094-9-160

Ejemplares similares

Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia
por: Becker, Esther B E, et al.
Publicado: (2012)

Onconeural antigen spreading in paraneoplastic neurological disease due to small cell lung cancer
por: Dik, Andre, et al.
Publicado: (2018)

Paraneoplastic and non-paraneoplastic autoimmunity to neurons in the central nervous system
por: Melzer, Nico, et al.
Publicado: (2012)

Paraneoplastic cerebellar ataxia with central hypoventilation
por: Kunchok, Amy, et al.
Publicado: (2016)

Evidence of a pathogenic role for CD8(+) T cells in anti-GABA(B) receptor limbic encephalitis
por: Golombeck, Kristin S., et al.
Publicado: (2016)

Paraneoplastic cerebellar ataxia in Merkel cell carcinoma of unknown primary
por: Queen, Dawn, et al.
Publicado: (2019)

CD4(+ )CD25(+ )FoxP3(+ )regulatory T cells suppress cytotoxicity of CD8(+ )effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level
por: Göbel, Kerstin, et al.
Publicado: (2012)

Septin-3 autoimmunity in patients with paraneoplastic cerebellar ataxia
por: Miske, Ramona, et al.
Publicado: (2023)

Primary B Cell Lymphoma of the CNS Mimicking Anti-LGI1 Limbic Encephalitis
por: Thomas, Christian, et al.
Publicado: (2018)

Paraneoplastic cerebellar ataxia and antibodies to metabotropic glutamate receptor 2
por: Ruiz-García, Raquel, et al.
Publicado: (2019)

Signatures of immune reprogramming in anti-CD52 therapy of MS: markers for risk stratification and treatment response
por: Bierhansl, Laura, et al.
Publicado: (2019)

Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8(+) T cell attack in the CNS gray matter
por: Melzer, Nico, et al.
Publicado: (2013)

Treating refractory post-herpetic anti-N-methyl-d-aspartate receptor encephalitis with rituximab
por: Strippel, Christine, et al.
Publicado: (2017)

Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease
por: Schröder, Jens B., et al.
Publicado: (2018)

Contactin-1 and contactin-2 in cerebrospinal fluid as potential biomarkers for axonal domain dysfunction in multiple sclerosis
por: Chatterjee, Madhurima, et al.
Publicado: (2018)

Spinal anaesthesia for a caesarean section in a patient with paraneoplastic cerebellar ataxia
por: Tuna, Ayca Tas, et al.
Publicado: (2017)

Contactin-associated protein 2 autoantibodies can be associated with multifocal motor-like neuropathy: a case report
por: Müller-Miny, Louisa, et al.
Publicado: (2023)

Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration
por: Miske, Ramona, et al.
Publicado: (2016)

Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses
por: Räuber, Saskia, et al.
Publicado: (2021)

Immune Cell Profiling of the Cerebrospinal Fluid Provides Pathogenetic Insights Into Inflammatory Neuropathies
por: Heming, Michael, et al.
Publicado: (2019)

Neurocognitive decline in HIV patients is associated with ongoing T-cell activation in the cerebrospinal fluid
por: Grauer, Oliver M, et al.
Publicado: (2015)

Update in Autoimmune Movement Disorders: Newly Described Antigen Targets in Autoimmune and Paraneoplastic Cerebellar Ataxia
por: Garza, Madeline, et al.
Publicado: (2021)

Immunophenotyping of cerebrospinal fluid cells by Chipcytometry
por: Hümmert, Martin W., et al.
Publicado: (2018)

Molecular and Cellular Substrates for the Friedreich Ataxia. Significance of Contactin Expression and of Antioxidant Administration
por: Bizzoca, Antonella, et al.
Publicado: (2020)

CD8(+) T Cell-Mediated Neuronal Dysfunction and Degeneration in Limbic Encephalitis
por: Ehling, Petra, et al.
Publicado: (2015)

Cerebrospinal fluid analysis in 108 patients with progressive multifocal leukoencephalopathy
por: Möhn, Nora, et al.
Publicado: (2020)

Phenotypic, Genomic and Functional Characterization Reveals No Differences between CD138(++) and CD138(low) Subpopulations in Multiple Myeloma Cell Lines
por: Paíno, Teresa, et al.
Publicado: (2014)

Treatment of Paraneoplastic Cerebellar Degeneration
por: Greenlee, John E.
Publicado: (2013)

Update on Paraneoplastic Cerebellar Degeneration
por: Loehrer, Philipp Alexander, et al.
Publicado: (2021)

Elevated Serum and Cerebrospinal Fluid CD138 in Patients With Anti-N-Methyl-d-Aspartate Receptor Encephalitis
por: Zhu, Jiajia, et al.
Publicado: (2019)

Syndecan-1 (CD138), Carcinomas and EMT
por: Couchman, John R.
Publicado: (2021)

Paraneoplastic Cerebellar Ataxia Can Affect Prognosis in High-Grade Serous Ovarian Cancer: A Case Report
por: Liapi, Aikaterini, et al.
Publicado: (2020)

Cerebrospinal Fluid Concentrations of Neuronal Proteins Are Reduced in Primary Angiitis of the Central Nervous System
por: Ruland, Tillmann, et al.
Publicado: (2018)

CD4(+)NKG2D(+) T Cells Exhibit Enhanced Migratory and Encephalitogenic Properties in Neuroinflammation
por: Ruck, Tobias, et al.
Publicado: (2013)

Correction: CD4(+)NKG2D(+) T Cells Exhibit Enhanced Migratory and Encephalitogenic Properties in Neuroinflammation
por: Ruck, Tobias, et al.
Publicado: (2013)

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
por: Schafflick, David, et al.
Publicado: (2020)

CD10 and CD138 can be expressed in giant cell tumor of bone: An immunohistochemical study
por: Al-Abbadi, Mousa A., et al.
Publicado: (2016)

Paraneoplastic cerebellar degeneration in Hodgkin's lymphoma
por: Suri, Vinit, et al.
Publicado: (2012)

Repetitive transcranial magnetic stimulation (rTMS) as a therapeutic option in paraneoplastic cerebellar ataxia – a case report
por: Jemna, Nicoleta, et al.
Publicado: (2022)

Paraneoplastic cerebellar degeneration associated with cerebellar hypermetabolism: Case report
por: Abdulaziz, Ammar Taha Abdullah, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2laqnpb4kq04ptnn69t45inj0q