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Biophysical assessment of DC iontophoresis and current density on transdermal permeation of methotrexate
INTRODUCTION: The effect of DC iontophoresis using low (0.2 mA/cm(2)) and high current density (0.5 mA/cm(2)) on transdermal permeation of methotrexate loaded into polyacrylamide hydrogel patch was investigated. RESULTS: Flux of 20.57 ± 1.02 μg/cm(2)/h and 36.8 ± 2.21 μg/cm(2)/h was achieved with lo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465143/ https://www.ncbi.nlm.nih.gov/pubmed/23071949 http://dx.doi.org/10.4103/2230-973X.93011 |