Prevention of Bone Growth Defects, Increased Bone Resorption and Marrow Adiposity with Folinic Acid in Rats Receiving Long-Term Methotrexate

The underlying pathophysiology for bone growth defects in paediatric cancer patients receiving high dose methotrexate chemotherapy remains unclear and currently there are no standardized preventative treatments for patients and survivors. Using a model in young rats, we investigated damaging effects...

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Detalles Bibliográficos
Autores principales: Fan, Chia-Ming, Foster, Bruce K., Hui, Susanta K., Xian, Cory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465278/
https://www.ncbi.nlm.nih.gov/pubmed/23071661
http://dx.doi.org/10.1371/journal.pone.0046915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465278/
https://www.ncbi.nlm.nih.gov/pubmed/23071661
http://dx.doi.org/10.1371/journal.pone.0046915

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