Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production

Oxidative damage and inflammation are proposed to be involved in an age-related functional decline of exocrine glands. However, the molecular mechanism of how oxidative stress affects the secretory function of exocrine glands is unclear. We developed a novel mev-1 conditional transgenic mouse model...

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Detalles Bibliográficos
Autores principales: Uchino, Yuichi, Kawakita, Tetsuya, Miyazawa, Masaki, Ishii, Takamasa, Onouchi, Hiromi, Yasuda, Kayo, Ogawa, Yoko, Shimmura, Shigeto, Ishii, Naoaki, Tsubota, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465290/
https://www.ncbi.nlm.nih.gov/pubmed/23071526
http://dx.doi.org/10.1371/journal.pone.0045805

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