Rare and Low Frequency Variant Stratification in the UK Population: Description and Impact on Association Tests

Although variations in allele frequencies at common SNPs have been extensively studied in different populations, little is known about the stratification of rare variants and its impact on association tests. In this paper, we used Affymetrix 500K genotype data from the WTCCC to investigate if varian...

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Detalles Bibliográficos
Autores principales: Babron, Marie-Claude, de Tayrac, Marie, Rutledge, Douglas N., Zeggini, Eleftheria, Génin, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465327/
https://www.ncbi.nlm.nih.gov/pubmed/23071581
http://dx.doi.org/10.1371/journal.pone.0046519

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