Cargando…

Regulation of NF-κB Activation through a Novel PI-3K-Independent and PKA/Akt-Dependent Pathway in Human Umbilical Vein Endothelial Cells

The transcription factor NF-κB regulates numerous inflammatory diseases, and proteins involved in the NF-κB-activating signaling pathway are important therapeutic targets. In human umbilical vein endothelial cells (HUVECs), TNF-α-induced IκBα degradation and p65/RelA phosphorylation regulate NF-κB a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balwani, Sakshi, Chaudhuri, Rituparna, Nandi, Debkumar, Jaisankar, Parasuraman, Agrawal, Anurag, Ghosh, Balaram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465347/ https://www.ncbi.nlm.nih.gov/pubmed/23071583 http://dx.doi.org/10.1371/journal.pone.0046528

Ejemplares similares

Regenerative abilities of mesenchymal stem cells through mitochondrial transfer
por: Paliwal, Swati, et al.
Publicado: (2018)

Human tissue-specific MSCs demonstrate differential mitochondria transfer abilities that may determine their regenerative abilities
por: Paliwal, Swati, et al.
Publicado: (2018)

Correction to: Human tissue-specific MSCs demonstrate differential mitochondria transfer abilities that may determine their regenerative abilities
por: Paliwal, Swati, et al.
Publicado: (2019)

The Anticoagulant Effect of PGI2S and tPA in Transgenic Umbilical Vein Endothelial Cells Is Linked to Up-Regulation of PKA and PKC
por: Wang, Jian-Hua, et al.
Publicado: (2014)

Desflurane Preconditioning Induces Oscillation of NF-κB in Human Umbilical Vein Endothelial Cells
por: Yi, Juan, et al.
Publicado: (2013)

Linoleic acid metabolite leads to steroid resistant asthma features partially through NF-κB
por: Panda, Lipsa, et al.
Publicado: (2017)

Secoisolariciresinol Diglucoside Exerts Anti-Inflammatory and Antiapoptotic Effects through Inhibiting the Akt/IκB/NF-κB Pathway on Human Umbilical Vein Endothelial Cells
por: Zhang, Shaoyang, et al.
Publicado: (2020)

Mechanistic Understanding of the Effect of Obesity on Asthma and Allergy
por: Agrawal, Anurag, et al.
Publicado: (2013)

Myristicin regulates proliferation and apoptosis in oxidized low-density lipoprotein-stimulated human vascular smooth muscle cells and human umbilical vein endothelial cells by regulating the PI3K/Akt/NF-κB signalling pathway
por: Luo, Liang, et al.
Publicado: (2021)

Effects of Simulated Microgravity on Human Umbilical Vein Endothelial Cell Angiogenesis and Role of the PI3K-Akt-eNOS Signal Pathway
por: Shi, Fei, et al.
Publicado: (2012)

Microcystins Induces Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Activation of NF-κB
por: Shi, Jun, et al.
Publicado: (2015)

Crotonylation of PRKACA enhances PKA activity and promotes colorectal cancer development via the PKA-FAK-AKT pathway
por: Hou, Jia-Yi, et al.
Publicado: (2022)

Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells
por: Niu, Haiming, et al.
Publicado: (2023)

Antioxidant Blueberry Anthocyanins Induce Vasodilation via PI3K/Akt Signaling Pathway in High-Glucose-Induced Human Umbilical Vein Endothelial Cells
por: Huang, Wuyang, et al.
Publicado: (2020)

Gastrodin prevents homocysteine‐induced human umbilical vein endothelial cells injury via PI3K/Akt/eNOS and Nrf2/ARE pathway
por: Chen, Jiyu, et al.
Publicado: (2020)

Synergistic Apoptosis of CML Cells by Buthionine Sulfoximine and Hydroxychavicol Correlates with Activation of AIF and GSH-ROS-JNK-ERK-iNOS Pathway
por: Chowdhury, Avik Acharya, et al.
Publicado: (2013)

Binding of the 9-O-N-aryl/arylalkyl Amino Carbonyl Methyl Substituted Berberine Analogs to tRNA(phe)
por: Basu, Anirban, et al.
Publicado: (2013)

MicroRNA-155 promotes ox-LDL-induced autophagy in human umbilical vein endothelial cells by targeting the PI3K/Akt/mTOR pathway
por: Yin, Shuangshuang, et al.
Publicado: (2018)

The up-regulation of miR-21 by gastrodin to promote the angiogenesis ability of human umbilical vein endothelial cells by activating the signaling pathway of PI3K/Akt
por: Wang, Jianli, et al.
Publicado: (2021)

Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway
por: Liu, Wei, et al.
Publicado: (2022)

The Rate of NF-κB Nuclear Translocation Is Regulated by PKA and A Kinase Interacting Protein 1
por: King, Charles C., et al.
Publicado: (2011)

The role of LRRK2 on PKA-NFκB pathway in microglia cells: implications for Parkinson’s disease
por: Russo, Isabella
Publicado: (2019)

NF-κB signaling is essential for resistance to heat stress-induced early stage apoptosis in human umbilical vein endothelial cells
por: Liu, Yanan, et al.
Publicado: (2015)

Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells
por: Cai, Guo-Long, et al.
Publicado: (2021)

Targeting the PI3K/AKT/mTOR/NFκB Axis in Ovarian Cancer
por: Ghoneum, Alia, et al.
Publicado: (2020)

Chemical O‐Glycosylations: An Overview
por: Das, Rituparna, et al.
Publicado: (2016)

Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways
por: Huang, Huey-Chun, et al.
Publicado: (2016)

Fermented Aronia melanocarpa Inhibits Melanogenesis through Dual Mechanisms of the PI3K/AKT/GSK-3β and PKA/CREB Pathways
por: Kim, Da Hee, et al.
Publicado: (2023)

Suppression of Apoptosis in Human Umbilical Vein Endothelial Cells (HUVECs) by Klotho Protein is Associated with Reduced Endoplasmic Reticulum Oxidative Stress and Activation of the PI3K/AKT Pathway
por: Cui, Wei, et al.
Publicado: (2018)

Hydrogen Sulfide Protects Against High Glucose-Induced Human Umbilical Vein Endothelial Cell Injury Through Activating PI3K/Akt/eNOS Pathway
por: Lin, Fengxia, et al.
Publicado: (2020)

Hæmaturia from Umbilical Vein; Constipation
por: Graham, O. W.
Publicado: (1898)

Prenatal Diagnosis of Aorta-Portal Vein-Umbilical Vein Anastomosis
por: Mathews, Basil, et al.
Publicado: (2019)

Prenatal Diagnosis of Aorta-Portal Vein-Umbilical Vein Anastomosis
por: Mathews, Basil, et al.
Publicado: (2019)

Amygdalin attenuates PM2.5-induced human umbilical vein endothelial cell injury via the TLR4/NF-κB and Bcl-2/Bax signaling pathways: Amygdalin on human umbilical vein endothelial cell injury
por: Wang, Bixu, et al.
Publicado: (2022)

Isorhamnetin Induces Melanoma Cell Apoptosis via the PI3K/Akt and NF-κB Pathways
por: Duan, Ran, et al.
Publicado: (2020)

6-Methylcoumarin Promotes Melanogenesis through the PKA/CREB, MAPK, AKT/PI3K, and GSK3β/β-Catenin Signaling Pathways
por: Kim, Taejin, et al.
Publicado: (2023)

Foetal death due to extensive extra-abdominal umbilical vein Varix with umbilical vein thrombosis: a case report
por: Song, Qing-Yun, et al.
Publicado: (2023)

Copper-azide nanoparticle: a ‘catalyst-cum-reagent’ for the designing of 5-alkynyl 1,4-disubstituted triazoles
por: Nandi, Debkumar, et al.
Publicado: (2020)

Comparison between mechanical properties of human saphenous vein and umbilical vein
por: Hamedani, Borhan Alhosseini, et al.
Publicado: (2012)

17β-estradiol upregulates striatin protein levels via Akt pathway in human umbilical vein endothelial cells
por: Zheng, Shuhui, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nfslgj0llneelcp97a2ohhg6g3