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Regulation of NF-κB Activation through a Novel PI-3K-Independent and PKA/Akt-Dependent Pathway in Human Umbilical Vein Endothelial Cells

The transcription factor NF-κB regulates numerous inflammatory diseases, and proteins involved in the NF-κB-activating signaling pathway are important therapeutic targets. In human umbilical vein endothelial cells (HUVECs), TNF-α-induced IκBα degradation and p65/RelA phosphorylation regulate NF-κB a...

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Detalles Bibliográficos
Autores principales:	Balwani, Sakshi, Chaudhuri, Rituparna, Nandi, Debkumar, Jaisankar, Parasuraman, Agrawal, Anurag, Ghosh, Balaram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465347/ https://www.ncbi.nlm.nih.gov/pubmed/23071583 http://dx.doi.org/10.1371/journal.pone.0046528

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