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Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

Detection of microbial products by host inflammasomes is critical for innate immune surveillance. Inflammasomes activate the CASPASE-1 (CASP1) protease, which processes the cytokines interleukin(IL)-1β and -18, and initiates a lytic host cell death called pyroptosis(1). To identify novel CASP1 funct...

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Detalles Bibliográficos
Autores principales:	von Moltke, Jakob, Trinidad, Norver J., Moayeri, Mahtab, Kintzer, Alexander F., Wang, Samantha B., van Rooijen, Nico, Brown, Charles R., Krantz, Bryan A., Leppla, Stephen H., Gronert, Karsten, Vance, Russell E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465483/ https://www.ncbi.nlm.nih.gov/pubmed/22902502 http://dx.doi.org/10.1038/nature11351

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