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Structural basis for RNA duplex recognition and unwinding by the DEAD-box helicase Mss116p
DEAD-box proteins are the largest family of nucleic acid helicases and are crucial to RNA metabolism throughout all domains of life(1,2). They contain a conserved ‘helicase core’ of two RecA-like domains (domains 1 and 2; D1 and D2, respectively), which uses ATP to catalyze the unwinding of short RN...
Autores principales: | Mallam, Anna L., Campo, Mark Del, Gilman, Benjamin, Sidote, David J., Lambowitz, Alan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465527/ https://www.ncbi.nlm.nih.gov/pubmed/22940866 http://dx.doi.org/10.1038/nature11402 |
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