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Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran

BACKGROUND AND OBJECTIVES: Group B Streptococci (GBS) is a major cause of neonatal and maternal infections. The aim of this study was to determine the serotype distribution and antibiotic resistance profile of GBS strains isolated from pregnant women in Ardabil. MATERIALS AND METHODS: Antibiotic res...

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Autores principales: Jannati, E, Roshani, M, Arzanlou, M, Habibzadeh, S, Rahimi, G, Shapuri, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465538/
https://www.ncbi.nlm.nih.gov/pubmed/23066487
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author Jannati, E
Roshani, M
Arzanlou, M
Habibzadeh, S
Rahimi, G
Shapuri, R
author_facet Jannati, E
Roshani, M
Arzanlou, M
Habibzadeh, S
Rahimi, G
Shapuri, R
author_sort Jannati, E
collection PubMed
description BACKGROUND AND OBJECTIVES: Group B Streptococci (GBS) is a major cause of neonatal and maternal infections. The aim of this study was to determine the serotype distribution and antibiotic resistance profile of GBS strains isolated from pregnant women in Ardabil. MATERIALS AND METHODS: Antibiotic resistance of 56 GBS isolates was investigated using E-test strips and disk-diffusion method. Serotyping was performed using capsular antiserum. RESULTS: The results of MIC tests showed all isolates were susceptible to ampicillin, vancomycin and penicillin. One isolate (1.7%) showed reduced susceptibility pattern to penicillin (MIC; 0.25 µg/ml). There were 3 (5.3%) isolates semi-sensitive (0.25-1 µg/ml) to erythromycin (2; 0.5 µg/ml and 1; 0.38 µg/ml) and 2 (3.5%) isolates to clindamycin (1; 0.5 µg/ml, 1; 0.38 µg/ml). Additionally, 2 (3.5%) isolates were resistant to clindamycin (1; 16 µg/ml, 1; 2 µg/ml). According to the disk diffusion test, 47 (83.9%), 8 (14.2%) and 7 (12.5%) isolates were resistant to Co-trimoxazole, ciprofloxacin and ceftriaxone respectively. Serotypes V (19.6%), II (12.5%) and IV (12.5%) were the most frequent followed by serotypes III (10.7%) and VI (10.7%), Ib (8.9%), Ia (7/1%), VII (5/3%) and VIII (5/3%); 7.1% of strains were nontypeable. CONCLUSIONS: In this study, most isolates were sensitive to common antibiotics, but increased resistance to other antibiotics indicates the importance of monitoring of antibiotic resistance in group B streptococci over time.
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spelling pubmed-34655382012-10-12 Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran Jannati, E Roshani, M Arzanlou, M Habibzadeh, S Rahimi, G Shapuri, R Iran J Microbiol Original Article BACKGROUND AND OBJECTIVES: Group B Streptococci (GBS) is a major cause of neonatal and maternal infections. The aim of this study was to determine the serotype distribution and antibiotic resistance profile of GBS strains isolated from pregnant women in Ardabil. MATERIALS AND METHODS: Antibiotic resistance of 56 GBS isolates was investigated using E-test strips and disk-diffusion method. Serotyping was performed using capsular antiserum. RESULTS: The results of MIC tests showed all isolates were susceptible to ampicillin, vancomycin and penicillin. One isolate (1.7%) showed reduced susceptibility pattern to penicillin (MIC; 0.25 µg/ml). There were 3 (5.3%) isolates semi-sensitive (0.25-1 µg/ml) to erythromycin (2; 0.5 µg/ml and 1; 0.38 µg/ml) and 2 (3.5%) isolates to clindamycin (1; 0.5 µg/ml, 1; 0.38 µg/ml). Additionally, 2 (3.5%) isolates were resistant to clindamycin (1; 16 µg/ml, 1; 2 µg/ml). According to the disk diffusion test, 47 (83.9%), 8 (14.2%) and 7 (12.5%) isolates were resistant to Co-trimoxazole, ciprofloxacin and ceftriaxone respectively. Serotypes V (19.6%), II (12.5%) and IV (12.5%) were the most frequent followed by serotypes III (10.7%) and VI (10.7%), Ib (8.9%), Ia (7/1%), VII (5/3%) and VIII (5/3%); 7.1% of strains were nontypeable. CONCLUSIONS: In this study, most isolates were sensitive to common antibiotics, but increased resistance to other antibiotics indicates the importance of monitoring of antibiotic resistance in group B streptococci over time. Tehran University of Medical Sciences 2012-09 /pmc/articles/PMC3465538/ /pubmed/23066487 Text en © 2012 Iranian Society of Microbiology & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jannati, E
Roshani, M
Arzanlou, M
Habibzadeh, S
Rahimi, G
Shapuri, R
Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran
title Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran
title_full Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran
title_fullStr Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran
title_full_unstemmed Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran
title_short Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran
title_sort capsular serotype and antibiotic resistance of group b streptococci isolated from pregnant women in ardabil, iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465538/
https://www.ncbi.nlm.nih.gov/pubmed/23066487
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