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Pre-existing virus-specific CD8(+) T-cells provide protection against pneumovirus-induced disease in mice

Pneumoviruses such as pneumonia virus of mice (PVM), bovine respiratory syncytial virus (bRSV) or human (h)RSV are closely related pneumoviruses that cause severe respiratory disease in their respective hosts. It is well-known that T-cell responses are essential in pneumovirus clearance, but pneumov...

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Detalles Bibliográficos
Autores principales: van Helden, Mary J.G., van Kooten, Peter J.S., Bekker, Cornelis P.J., Gröne, Andrea, Topham, David J., Easton, Andrew J., Boog, Claire J.P., Busch, Dirk H., Zaiss, Dietmar M.W., Sijts, Alice J.A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465553/
https://www.ncbi.nlm.nih.gov/pubmed/22940382
http://dx.doi.org/10.1016/j.vaccine.2012.08.027