Cargando…

Diabetic angiopathy and angiogenic defects

Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits an...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Ling, Kanasaki, Keizo, Kitada, Munehiro, Koya, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465576/
https://www.ncbi.nlm.nih.gov/pubmed/22853690
http://dx.doi.org/10.1186/1755-1536-5-13
_version_ 1782245571739779072
author Xu, Ling
Kanasaki, Keizo
Kitada, Munehiro
Koya, Daisuke
author_facet Xu, Ling
Kanasaki, Keizo
Kitada, Munehiro
Koya, Daisuke
author_sort Xu, Ling
collection PubMed
description Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits and drawbacks as a therapeutic target for diabetic vascular complications. Additionally, we discuss glucose metabolism defects that are associated with abnormal angiogenesis in atypical diabetic complications such as cancer.
format Online
Article
Text
id pubmed-3465576
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-34655762012-10-07 Diabetic angiopathy and angiogenic defects Xu, Ling Kanasaki, Keizo Kitada, Munehiro Koya, Daisuke Fibrogenesis Tissue Repair Review Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits and drawbacks as a therapeutic target for diabetic vascular complications. Additionally, we discuss glucose metabolism defects that are associated with abnormal angiogenesis in atypical diabetic complications such as cancer. BioMed Central 2012-08-01 /pmc/articles/PMC3465576/ /pubmed/22853690 http://dx.doi.org/10.1186/1755-1536-5-13 Text en Copyright ©2012 Xu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Xu, Ling
Kanasaki, Keizo
Kitada, Munehiro
Koya, Daisuke
Diabetic angiopathy and angiogenic defects
title Diabetic angiopathy and angiogenic defects
title_full Diabetic angiopathy and angiogenic defects
title_fullStr Diabetic angiopathy and angiogenic defects
title_full_unstemmed Diabetic angiopathy and angiogenic defects
title_short Diabetic angiopathy and angiogenic defects
title_sort diabetic angiopathy and angiogenic defects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465576/
https://www.ncbi.nlm.nih.gov/pubmed/22853690
http://dx.doi.org/10.1186/1755-1536-5-13
work_keys_str_mv AT xuling diabeticangiopathyandangiogenicdefects
AT kanasakikeizo diabeticangiopathyandangiogenicdefects
AT kitadamunehiro diabeticangiopathyandangiogenicdefects
AT koyadaisuke diabeticangiopathyandangiogenicdefects