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Diabetic angiopathy and angiogenic defects
Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465576/ https://www.ncbi.nlm.nih.gov/pubmed/22853690 http://dx.doi.org/10.1186/1755-1536-5-13 |
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author | Xu, Ling Kanasaki, Keizo Kitada, Munehiro Koya, Daisuke |
author_facet | Xu, Ling Kanasaki, Keizo Kitada, Munehiro Koya, Daisuke |
author_sort | Xu, Ling |
collection | PubMed |
description | Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits and drawbacks as a therapeutic target for diabetic vascular complications. Additionally, we discuss glucose metabolism defects that are associated with abnormal angiogenesis in atypical diabetic complications such as cancer. |
format | Online Article Text |
id | pubmed-3465576 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34655762012-10-07 Diabetic angiopathy and angiogenic defects Xu, Ling Kanasaki, Keizo Kitada, Munehiro Koya, Daisuke Fibrogenesis Tissue Repair Review Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits and drawbacks as a therapeutic target for diabetic vascular complications. Additionally, we discuss glucose metabolism defects that are associated with abnormal angiogenesis in atypical diabetic complications such as cancer. BioMed Central 2012-08-01 /pmc/articles/PMC3465576/ /pubmed/22853690 http://dx.doi.org/10.1186/1755-1536-5-13 Text en Copyright ©2012 Xu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Xu, Ling Kanasaki, Keizo Kitada, Munehiro Koya, Daisuke Diabetic angiopathy and angiogenic defects |
title | Diabetic angiopathy and angiogenic defects |
title_full | Diabetic angiopathy and angiogenic defects |
title_fullStr | Diabetic angiopathy and angiogenic defects |
title_full_unstemmed | Diabetic angiopathy and angiogenic defects |
title_short | Diabetic angiopathy and angiogenic defects |
title_sort | diabetic angiopathy and angiogenic defects |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465576/ https://www.ncbi.nlm.nih.gov/pubmed/22853690 http://dx.doi.org/10.1186/1755-1536-5-13 |
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