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Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER stress response, resulting in reduced adiponectin synthesis in adipocytes. The expression of inducibl...

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Detalles Bibliográficos
Autores principales: Jeon, Min Jae, Leem, Jaechan, Ko, Myoung Seok, Jang, Jung Eun, Park, Hye-Sun, Kim, Hyun Sik, Kim, Mina, Kim, Eun Hee, Yoo, Hyun Ju, Lee, Chul-Ho, Park, In-Sun, Lee, Ki-Up, Koh, Eun Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465750/
https://www.ncbi.nlm.nih.gov/pubmed/22809900
http://dx.doi.org/10.3858/emm.2012.44.9.064