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Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER stress response, resulting in reduced adiponectin synthesis in adipocytes. The expression of inducibl...
Autores principales: | Jeon, Min Jae, Leem, Jaechan, Ko, Myoung Seok, Jang, Jung Eun, Park, Hye-Sun, Kim, Hyun Sik, Kim, Mina, Kim, Eun Hee, Yoo, Hyun Ju, Lee, Chul-Ho, Park, In-Sun, Lee, Ki-Up, Koh, Eun Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465750/ https://www.ncbi.nlm.nih.gov/pubmed/22809900 http://dx.doi.org/10.3858/emm.2012.44.9.064 |
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