In vivo Selection of Autologous MGMT Gene-Modified Cells Following Reduced Intensity Conditioning with BCNU and Temozolomide in the Dog Model

Chemotherapy with BCNU and temozolomide (TMZ) is commonly used for the treatment of glioblastoma multiforme (GBM) and other cancers. In preparation for a clinical gene therapy study in patients with glioblastoma, we wished to study whether these reagents could be used as a reduced-intensity conditio...

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Detalles Bibliográficos
Autores principales: Gori, Jennifer L., Beard, Brian C., Ironside, Christina, Karponi, Garyfalia, Kiem, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466091/
https://www.ncbi.nlm.nih.gov/pubmed/22627392
http://dx.doi.org/10.1038/cgt.2012.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466091/
https://www.ncbi.nlm.nih.gov/pubmed/22627392
http://dx.doi.org/10.1038/cgt.2012.25

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