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The CRISPR Associated Protein Cas4 Is a 5′ to 3′ DNA Exonuclease with an Iron-Sulfur Cluster

The Cas4 protein is one of the core CRISPR-associated (Cas) proteins implicated in the prokaryotic CRISPR system for antiviral defence. Cas4 is thought to play a role in the capture of new viral DNA sequences for incorporation into the host genome. No biochemical activity has been reported for Cas4,...

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Detalles Bibliográficos
Autores principales:	Zhang, Jing, Kasciukovic, Taciana, White, Malcolm F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466216/ https://www.ncbi.nlm.nih.gov/pubmed/23056615 http://dx.doi.org/10.1371/journal.pone.0047232

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