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Handling Missing Data in Transmission Disequilibrium Test in Nuclear Families with One Affected Offspring
The Transmission Disequilibrium Test (TDT) compares frequencies of transmission of two alleles from heterozygote parents to an affected offspring. This test requires all genotypes to be known from all members of the nuclear families. However, obtaining all genotypes in a study might not be possible...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466247/ https://www.ncbi.nlm.nih.gov/pubmed/23056239 http://dx.doi.org/10.1371/journal.pone.0046100 |