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Handling Missing Data in Transmission Disequilibrium Test in Nuclear Families with One Affected Offspring

The Transmission Disequilibrium Test (TDT) compares frequencies of transmission of two alleles from heterozygote parents to an affected offspring. This test requires all genotypes to be known from all members of the nuclear families. However, obtaining all genotypes in a study might not be possible...

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Detalles Bibliográficos
Autor principal:	Bourget, Gulhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466247/ https://www.ncbi.nlm.nih.gov/pubmed/23056239 http://dx.doi.org/10.1371/journal.pone.0046100

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