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Expression of Plasmid-Based shRNA against the E1 and nsP1 Genes Effectively Silenced Chikungunya Virus Replication

BACKGROUND: Chikungunya virus (CHIKV) is a re-emerging alphavirus that causes chikungunya fever and persistent arthralgia in humans. Currently, there is no effective vaccine or antiviral against CHIKV infection. Therefore, this study evaluates whether RNA interference which targets at viral genomic...

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Detalles Bibliográficos
Autores principales:	Lam, Shirley, Chen, Karen Caiyun, Ng, Mary Mah-Lee, Chu, Justin Jang Hann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466284/ https://www.ncbi.nlm.nih.gov/pubmed/23056297 http://dx.doi.org/10.1371/journal.pone.0046396

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