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Conjugation of Proteins by Installing BIO-Orthogonally Reactive Groups at Their N-Termini
N-terminal site-specific modification of a protein has many advantages over methods targeting internal positions, but it is not easy to install reactive groups onto a protein in an N-terminal specific manner. We here report a strategy to incorporate amino acid analogues specifically in the N-terminu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466299/ https://www.ncbi.nlm.nih.gov/pubmed/23056430 http://dx.doi.org/10.1371/journal.pone.0046741 |