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(−)-Epigallocatechin-3-Gallate Induces Non-Apoptotic Cell Death in Human Cancer Cells via ROS-Mediated Lysosomal Membrane Permeabilization

(−)-Epigallocatechin-3-gallate (EGCG) is the most extensive studied tea polyphenol for its anti-cancer function. In this study, we report a novel mechanism of action for EGCG-mediated cell death by identifying the critical role of lysosomal membrane permeabilization (LMP). First, EGCG-induced cell d...

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Detalles Bibliográficos
Autores principales:	Zhang, Yin, Yang, Nai-Di, Zhou, Fan, Shen, Ting, Duan, Ting, Zhou, Jing, Shi, Yin, Zhu, Xin-Qiang, Shen, Han-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466311/ https://www.ncbi.nlm.nih.gov/pubmed/23056433 http://dx.doi.org/10.1371/journal.pone.0046749

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