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An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes
During liver regeneration, quiescent hepatocytes re-enter the cell cycle to proliferate and compensate for lost tissue. Multiple signals including hepatocyte growth factor, epidermal growth factor, tumor necrosis factor α, interleukin-6, insulin and transforming growth factor β orchestrate these res...
Autores principales: | Huard, Jérémy, Mueller, Stephanie, Gilles, Ernst D, Klingmüller, Ursula, Klamt, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466406/ https://www.ncbi.nlm.nih.gov/pubmed/22443451 http://dx.doi.org/10.1111/j.1742-4658.2012.08572.x |
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