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An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes

During liver regeneration, quiescent hepatocytes re-enter the cell cycle to proliferate and compensate for lost tissue. Multiple signals including hepatocyte growth factor, epidermal growth factor, tumor necrosis factor α, interleukin-6, insulin and transforming growth factor β orchestrate these res...

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Detalles Bibliográficos
Autores principales: Huard, Jérémy, Mueller, Stephanie, Gilles, Ernst D, Klingmüller, Ursula, Klamt, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466406/
https://www.ncbi.nlm.nih.gov/pubmed/22443451
http://dx.doi.org/10.1111/j.1742-4658.2012.08572.x

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