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Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

Angiotensin-I converting enzyme (ACE), a two-domain dipeptidylcarboxypeptidase, is a key regulator of blood pressure as a result of its critical role in the renin-angiotensin-aldosterone and kallikrein-kinin systems. Hence it is an important drug target in the treatment of cardiovascular diseases. A...

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Detalles Bibliográficos
Autores principales:	Masuyer, Geoffrey, Schwager, Sylva L. U., Sturrock, Edward D., Isaac, R. Elwyn, Acharya, K. Ravi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466449/ https://www.ncbi.nlm.nih.gov/pubmed/23056909 http://dx.doi.org/10.1038/srep00717

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