Metabolic remodeling of the tumor microenvironment: Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth

Migration stimulating factor (MSF) is a genetically truncated N-terminal isoform of fibronectin that is highly expressed during mammalian development in fetal fibroblasts, and during tumor formation in human cancer-associated myofibroblasts. However, its potential functional role in regulating tumor...

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Detalles Bibliográficos
Autores principales: Carito, Valentina, Bonuccelli, Gloria, Martinez-Outschoorn, Ubaldo E., Whitaker-Menezes, Diana, Caroleo, Maria Cristina, Cione, Erika, Howell, Anthony, Pestell, Richard G., Lisanti, Michael P., Sotgia, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466551/
https://www.ncbi.nlm.nih.gov/pubmed/22918248
http://dx.doi.org/10.4161/cc.21701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466551/
https://www.ncbi.nlm.nih.gov/pubmed/22918248
http://dx.doi.org/10.4161/cc.21701

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