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Metabolic remodeling of the tumor microenvironment: Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth
Migration stimulating factor (MSF) is a genetically truncated N-terminal isoform of fibronectin that is highly expressed during mammalian development in fetal fibroblasts, and during tumor formation in human cancer-associated myofibroblasts. However, its potential functional role in regulating tumor...
Autores principales: | Carito, Valentina, Bonuccelli, Gloria, Martinez-Outschoorn, Ubaldo E., Whitaker-Menezes, Diana, Caroleo, Maria Cristina, Cione, Erika, Howell, Anthony, Pestell, Richard G., Lisanti, Michael P., Sotgia, Federica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466551/ https://www.ncbi.nlm.nih.gov/pubmed/22918248 http://dx.doi.org/10.4161/cc.21701 |
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