The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

Fibroblast growth factor-21 (FGF21) is a hormone secreted by the liver during fasting that elicits diverse aspects of the adaptive starvation response. Among its effects, FGF21 induces hepatic fatty acid oxidation and ketogenesis, increases insulin sensitivity, blocks somatic growth and causes bone...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Xie, Yang, Berglund, Eric D, Coate, Katie Colbert, He, Tian Teng, Katafuchi, Takeshi, Xiao, Guanghua, Potthoff, Matthew J, Wei, Wei, Wan, Yihong, Yu, Ruth T, Evans, Ronald M, Kliewer, Steven A, Mangelsdorf, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466591/
https://www.ncbi.nlm.nih.gov/pubmed/23066506
http://dx.doi.org/10.7554/eLife.00065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466591/
https://www.ncbi.nlm.nih.gov/pubmed/23066506
http://dx.doi.org/10.7554/eLife.00065

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