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Urea–Water Solvation Forces on Prion Structures

Solvation forces are crucial determinants in the equilibrium between the folded and unfolded state of proteins. Particularly interesting are the solvent forces of denaturing solvent mixtures on folded and misfolded states of proteins involved in neurodegeneration. The C-terminal globular domain of t...

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Detalles Bibliográficos
Autores principales: Kleinjung, Jens, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466777/
https://www.ncbi.nlm.nih.gov/pubmed/23066353
http://dx.doi.org/10.1021/ct300264w

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