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Phosphorothioate DNA as an antioxidant in bacteria

Diverse bacteria contain DNA with sulfur incorporated stereo-specifically into their DNA backbone at specific sequences (phosphorothioation). We found that in vitro oxidation of phosphorothioate (PT) DNA by hydrogen peroxide (H(2)O(2)) or peracetic acid has two possible outcomes: DNA backbone cleava...

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Detalles Bibliográficos
Autores principales:	Xie, Xinqiang, Liang, Jingdan, Pu, Tianning, Xu, Fei, Yao, Fen, Yang, Yan, Zhao, Yi-Lei, You, Delin, Zhou, Xiufen, Deng, Zixin, Wang, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467049/ https://www.ncbi.nlm.nih.gov/pubmed/22772986 http://dx.doi.org/10.1093/nar/gks650

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