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Group I mGluR antagonist rescues the deficit of D1-induced LTP in a mouse model of fragile X syndrome

BACKGROUND: Fragile X syndrome (FXS) is caused by the absence of the mRNA-binding protein Fragile X mental retardation protein (FMRP), encoded by the Fmr1 gene. Overactive signaling by group 1 metabotropic glutamate receptor (Grp1 mGluR) could contribute to slowed synaptic development and other symp...

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Detalles Bibliográficos
Autores principales:	Xu, Zhao-Hui, Yang, Qi, Feng, Bin, Liu, Shui-bing, Zhang, Nan, Xing, Jiang-hao, Li, Xiao-Qiang, Wu, Yu-mei, Gao, Guo-Dong, Zhao, Ming-Gao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467183/ https://www.ncbi.nlm.nih.gov/pubmed/22640474 http://dx.doi.org/10.1186/1750-1326-7-24

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