Global Changes in the Rat Heart Proteome Induced by Prolonged Morphine Treatment and Withdrawal

Morphine belongs among the most commonly used opioids in medical practice due to its strong analgesic effects. However, sustained administration of morphine leads to the development of tolerance and dependence and may cause long-lasting alterations in nervous tissue. Although proteomic approaches en...

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Detalles Bibliográficos
Autores principales: Drastichova, Zdenka, Skrabalova, Jitka, Jedelsky, Petr, Neckar, Jan, Kolar, Frantisek, Novotny, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467212/
https://www.ncbi.nlm.nih.gov/pubmed/23056601
http://dx.doi.org/10.1371/journal.pone.0047167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467212/
https://www.ncbi.nlm.nih.gov/pubmed/23056601
http://dx.doi.org/10.1371/journal.pone.0047167

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