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Global Changes in the Rat Heart Proteome Induced by Prolonged Morphine Treatment and Withdrawal
Morphine belongs among the most commonly used opioids in medical practice due to its strong analgesic effects. However, sustained administration of morphine leads to the development of tolerance and dependence and may cause long-lasting alterations in nervous tissue. Although proteomic approaches en...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467212/ https://www.ncbi.nlm.nih.gov/pubmed/23056601 http://dx.doi.org/10.1371/journal.pone.0047167 |