Increased Synapse Formation Obtained by T Cell Epitopes Containing a CxxC Motif in Flanking Residues Convert CD4+ T Cells into Cytolytic Effectors

The nature of MHC class II-binding epitopes not only determines the specificity of T cell responses, but may also alter effector cell functions. Cytolytic CD4+ T cells have been observed primarily in anti-viral responses, but very little is known about the conditions under which they can be elicited...

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Detalles Bibliográficos
Autores principales: Carlier, Vincent A., VanderElst, Luc, Janssens, Wim, Jacquemin, Marc G., Saint-Remy, Jean-Marie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467281/
https://www.ncbi.nlm.nih.gov/pubmed/23056200
http://dx.doi.org/10.1371/journal.pone.0045366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467281/
https://www.ncbi.nlm.nih.gov/pubmed/23056200
http://dx.doi.org/10.1371/journal.pone.0045366

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